Kanna may have been used for centuries as a mood enhancer and more recently as a possible treatment for depression, like its relative St.John’s wort.
While Kanna has shown to be very safe for healthy adults. There are some potential side effects that could occur if someone were to mix Kanna with certain medications.
Please read the cautions below for more information.
This information is for educational purposes only and may or may not be supported by scientific studies.
We offer Kanna for no intention or purpose.
Botanical Name: Sceletium Tortuosum
Plant Family: Aizoaceae
Also Called: Kauwgoed, Kougoed and Canna.
Sceletium tortuosum a small groundcover plant native to Southern Africa has written records of use dating back to 1662 when Kanna was a bartering currency. Traditionally the prepared dried plant material was chewed and the saliva swallowed but it has also been made into teas and tinctures and inhaled as a snuff, or smoked.
Chemistry and Pharmacology
The mood-elevating action of kanna is caused by a number of alkaloids including mesembrine, mesembrenol and tortuosamine which interact with the brain’s dopamine and serotonin receptors. Mesembrine is a major alkaloid present in Sceletium. Mesembrine has been demonstrated to be a potent serotonin uptake inhibitor. This receptor specific activity, and receptor activities are also found on nicotinic, dopamine and nor-adrenaline areas certainly validate the traditional mood-elevating uses, and suggest additional therapeutic and wellness potential.
For hundreds of years the Hottentots of Southern Africa may have used Kanna: Sceletium tortuosum as a mood elevator, relaxant and empathogen. When chewed Kanna may have a mild aneasthetic effect in the mouth, much like kava, and may be used by the San tribes if you are about to have a tooth extracted. Kanna may have been added to a teaspoon of breast milk as a treatment for colic in infants. A tea made from Sceletium may sometimes be used to wean alcoholics off alcohol. Tablets and capsules of Sceletium are being used successfully by a number of psychiatrists, psychologists and doctors with excellent results for anxiety states and mild to moderate depression.
There have been no confirmed reports of drug interactions, However, because of the nero-receptor activities of Sceletium there may be interactions with other pharmacokinetiv drugs. People taking any psychiatric drug (including all anti-anxiety drugs, sedatives, hypnotics, antidepressants and anti-psychotics and so-called designer or recreational drugs) or any cardiac medications, are advised not to take Sceletium-containing products. As with most supplements and modern drugs, safety in pregnancy has not been established.
Very few people experience side-effects. The reported side-effects include: Mild headache, Slight nausea- no vomiting, Soft stool or loose stool with no cramping, Transient increase in anxiety or irritability an hour after initiating treatment,,Insomnia: corrected by lowering the dose or taking the product not later than midday,a feeling of sedation: corrected by taking the product as a single 50mg dose at night.
NO severe side effects have ever been documented.
Some herbs may have interactions with pregnancy, nursing or medications. Pregnant or nursing women & persons with health problems must consult a physician before use. The statements above have not been evaluated by the Food and Drug Administration.
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